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Cholate—CoA ligase
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Cholate—CoA ligase : ウィキペディア英語版
Cholate—CoA ligase

Cholate—CoA ligase (, ''BAL'', ''bile acid CoA ligase'', ''bile acid coenzyme A ligase'', ''choloyl-CoA synthetase'', ''choloyl coenzyme A synthetase'', ''cholic thiokinase'', ''cholate thiokinase'', ''cholic acid:CoA ligase'', ''3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoyl coenzyme A synthetase'', ''3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoate-CoA ligase'', ''3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoate-CoA synthetase'', ''THCA-CoA ligase'', ''3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanate—CoA ligase'', ''3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanate:CoA ligase (AMP-forming)'', ''cholyl-CoA synthetase'', ''trihydroxycoprostanoyl-CoA synthetase'') is an enzyme with system name ''cholate:CoA ligase (AMP-forming)''. This enzyme catalyses the following chemical reaction
: (1) ATP + cholate + CoA \rightleftharpoons AMP + diphosphate + choloyl-CoA
: (2) ATP + (25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oate + CoA \rightleftharpoons AMP + diphosphate + (25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoyl-CoA
This enzyme requires Mg2+ for activity.
== References ==


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